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Beilstein J. Org. Chem. 2017, 13, 552–557, doi:10.3762/bjoc.13.53
Graphical Abstract
Scheme 1: Representative examples of bioactive compounds bearing a propargylamine moiety and synthesis of var...
Scheme 2: Various metal-catalyzed methods for the synthesis of propargylamine.
Figure 1: Synthesis of various propargylamines from various salicylaldehydes under metal-catalyst-free condit...
Scheme 3: Plausible mechanism for the metal-free A3 coupling from salicylaldehyde.